
"Your 8 year child wakes up on Monday morning and says she has a stomach ache"
How would you diagnose and troubleshoot this situation?
Child says:
"My stomach hurts."
│
▼
Does the child have a fever?
├──────────────┐
Yes No
│ │
▼ ▼
Possible illness Is today Monday morning?
Keep home / doctor ├──────────────┐
Yes No
│ │
▼ ▼
Did the child ask Ate something
to stay home? unusual?
├───────┐ ├───────┐
Yes No Yes No
│ │ │ │
▼ ▼ ▼ ▼
Possible school Go to Observe Mild stomach
avoidance school at home upset

Symptom Checker with Body from WebMD - Check Your Medical Symptoms

Uses: Sequential Decision Making


Can we move beyond "if- then" encoding of our own judgement and make the machine actually learn something
Machine learning is a method of training computers to find patterns in data and make predictions or decisions without being explicitly programmed for every rule. It improves as it sees more data and feedback.


A phone recognizes your fingerprint (to unlock) because it has learned visual patterns.
Spotify or TikTok recommends content because it has learned patterns in behavior.
Netflix may know your movie preference better than you!!!
Waze knows
Your airport has received €1,000,000 to build one Machine Learning system that will improve passenger security while reducing waiting times.
You have 10 minutes to prepare a proposal for the airport board.
Your goal is not to build the AI.
Your goal is to ....
Data
THE ECONOMIST unlocking-enterprise-ai.pdf
Bias in ML: Implication and Sources
AI Bias: 16 Real AI Bias Examples & Mitigation Guide Joel Bervell, MD on Instagram: "Racial Bias in Medicine Episode 1: Pulse Oximeters I’m bringing back my “Racial Bias in Medicine” series and adding updates about the changes that have, and have not be COMPAS : Unfair Algorithm ?
Emergent strategy, minimal rules, maximizing rewards and learning through repeated self play


We've seen that ML can Classify, Cluster, or Act/Decide. But how does the machine actually compute all of this at scale? The answer is Neural Networks — the computational engine that powers all three learning strategies.
Neural networks process various inputs to generate specific outputs. While the inputs and outputs are clear, the intricate connections and transformations within the hidden layers make the internal decision-making process incredibly complex and often inexplicable. This characteristic is often referred to as the "black box" problem, highlighting the challenge of understanding how the network arrives at its conclusions.

Suppose Waze wants to predict
"How many minutes will it take to drive this road?"
Inputs might include
Output
The Economist reported that it used 1,920 CPUs and 280 GPUs:
(about 2000Terraflops or 1000 iphone16s)



Targeted Oncology
AlphaFold AI Sets Stage for Future Approaches in Cancer
The 2024 Nobel Prize in Chemistry highlights AI-driven breakthroughs in computational protein design and structure prediction. Tools like AlphaFold promise faster development of targeted cancer drugs and transformative advances in oncology and medicine.
shap.readthedocs.io
An introduction to explainable AI with Shapley values — SHAP latest documentation
This is an introduction to explaining machine learning models with Shapley values. Shapley values are a widely used approach from cooperative game theory that come with desirable properties. This tutorial is designed to help build a solid understanding of how to compute and interpet Shapley-based explanations of machine learning models. We will take a practical hands-on approach, using the shap Python package to explain progressively more complex models. This is a living document, and serves as




Are we asking the right questions?
Are we testing out of sample?
Are we prepared to deal with probabilistic results?

The training data does not include a situation that you want it to answer